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Focal Chromosomal Copy Number Aberrations Identify CMTM8 and GPR177 as New Candidate Driver Genes in Osteosarcoma

Osteosarcoma is an aggressive bone tumor that preferentially develops in adolescents. The tumor is characterized by an abundance of genomic aberrations, which hampers the identification of the driver genes involved in osteosarcoma tumorigenesis. Our study aims to identify these genes by the investig...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Both, Joeri, Krijgsman, Oscar, Bras, Johannes, Schaap, Gerard R., Baas, Frank, Ylstra, Bauke, Hulsebos, Theo J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281204/
https://ncbi.nlm.nih.gov/pubmed/25551557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115835
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