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Identification of nuclear hormone receptor pathways causing insulin resistance by transcriptional and epigenomic analysis

Insulin resistance is a sine qua non of Type 2 diabetes (T2D) and a frequent complication of multiple clinical conditions, including obesity, aging, and steroid use, among others. How such a panoply of insults can result in a common phenotype is incompletely understood. Furthermore, very little is k...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Kang, Sona, Tsai, Linus T., Zhou, Yiming, Evertts, Adam, Xu, Su, Griffin, Michael J., Issner, Robbyn, Whitton, Holly J., Garcia, Benjamin A., Epstein, Charles B., Mikkelsen, Tarjei S., Rosen, Evan D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281178/
https://ncbi.nlm.nih.gov/pubmed/25503565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3080
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