Yokukansan, a Kampo Medicine, Protects PC12 Cells from Glutamate-Induced Death by Augmenting Gene Expression of Cystine/Glutamate Antiporter System Xc(−)

Effects of the kampo medicine yokukansan on gene expression of the cystine/glutamate antiporter system Xc(−), which protects against glutamate-induced cytotoxicity, were examined in Pheochromocytoma cells (PC12 cells). Yokukansan inhibited glutamate-induced PC12 cell death. Similar cytoprotective ef...

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Bibliographic Details
Published in:PLoS One
Main Authors: Kanno, Hitomi, Kawakami, Zenji, Mizoguchi, Kazushige, Ikarashi, Yasushi, Kase, Yoshio
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281137/
https://ncbi.nlm.nih.gov/pubmed/25551766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116275
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