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Signals from the surface modulate differentiation of human pluripotent stem cells through glycosaminoglycans and integrins
The fate decisions of human pluripotent stem (hPS) cells are governed by soluble and insoluble signals from the microenvironment. Many hPS cell differentiation protocols use Matrigel, a complex and undefined substrate that engages multiple adhesion and signaling receptors. Using defined surfaces pro...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4280649/ https://ncbi.nlm.nih.gov/pubmed/25422477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409525111 |
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