Inflammatory sensitization of nociceptors depends on activation of NMDA receptors in DRG satellite cells

The present study evaluated the role of N-methyl-d-aspartate receptors (NMDARs) expressed in the dorsal root ganglia (DRG) in the inflammatory sensitization of peripheral nociceptor terminals to mechanical stimulation. Injection of NMDA into the fifth lumbar (L5)-DRG induced hyperalgesia in the rat...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Ferrari, Luiz Fernando, Lotufo, Celina Monteiro, Araldi, Dionéia, Rodrigues, Marcos A., Macedo, Larissa P., Ferreira, Sérgio H., Parada, Carlos Amilcar
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280647/
https://ncbi.nlm.nih.gov/pubmed/25489099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420601111
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