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Systematic engineering of 3D pluripotent stem cell niches to guide blood development

Pluripotent stem cells (PSC) provide insight into development and may underpin new cell therapies, yet controlling PSC differentiation to generate functional cells remains a significant challenge. In this study we explored the concept that mimicking the local in vivo microenvironment during mesoderm...

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Détails bibliographiques
Publié dans:Biomaterials
Auteurs principaux: Purpura, Kelly A., Bratt-Leal, Andrés M., Hammersmith, Katy A., McDevitt, Todd C., Zandstra, Peter W.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280365/
https://ncbi.nlm.nih.gov/pubmed/22079776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.10.051
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