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Systematic engineering of 3D pluripotent stem cell niches to guide blood development

Pluripotent stem cells (PSC) provide insight into development and may underpin new cell therapies, yet controlling PSC differentiation to generate functional cells remains a significant challenge. In this study we explored the concept that mimicking the local in vivo microenvironment during mesoderm...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Purpura, Kelly A., Bratt-Leal, Andrés M., Hammersmith, Katy A., McDevitt, Todd C., Zandstra, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280365/
https://ncbi.nlm.nih.gov/pubmed/22079776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.10.051
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