Graphene Nanoribbons as a Drug Delivery Agent for Lucanthone Mediated Therapy of Glioblastoma Multiforme

We report use of PEG-DSPE coated oxidized graphene nanoribbons (O-GNR-PEG-DSPE) as agent for delivery of anti-tumor drug Lucanthone (Luc) into Glioblastoma Multiformae (GBM) cells targeting base excision repair enzyme APE-1 (Apurinic endonuclease-1). Lucanthone, an endonuclease inhibitor of APE-1, w...

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Publicat a:Nanomedicine
Autors principals: Chowdhury, Sayan Mullick, Surhland, Cassandra, Sanchez, Zina, Chaudhary, Pankaj, Kumar, M.A. Suresh, Lee, Stephen, Peña, Louis A., Waring, Michael, Sitharaman, Balaji, Naidu, Mamta
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280300/
https://ncbi.nlm.nih.gov/pubmed/25131339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2014.08.001
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