Poor Warfarin Dose Prediction with Pharmacogenetic Algorithms that Exclude Genotypes Important for African Americans

OBJECTIVES: Recent clinical trial data cast doubt on the utility of genotype-guided warfarin dosing, specifically showing worse dosing with a pharmacogenetic versus clinical dosing algorithm in African Americans. However, many genotypes important in African Americans were not accounted for. We aimed...

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Bibliographic Details
Published in:Pharmacogenet Genomics
Main Authors: Drozda, Katarzyna, Wong, Shan, Patel, Shitalben R., Bress, Adam P., Nutescu, Edith A., Kittles, Rick A., Cavallari, Larisa H.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280295/
https://ncbi.nlm.nih.gov/pubmed/25461246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000108
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