HET0016, a Selective Inhibitor of 20-HETE Synthesis, Decreases Pro-Angiogenic Factors and Inhibits Growth of Triple Negative Breast Cancer in Mice

A selective inhibitor of 20-HETE synthesis, HET0016, has been reported to inhibit angiogenesis. 20-HETE has been known as a second mitogenic messenger of angiogenesis inducing growth factors. HET0016 effects were analyzed on MDA-MB-231 derived breast cancer in mouse and in vitro cell line. MDA-MB-23...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Borin, Thaiz Ferraz, Zuccari, Debora A. P. C., Jardim-Perassi, Bruna V., Ferreira, Lívia C., Iskander, A. S. M., Varma, Nadimpalli Ravi S., Shankar, Adarsh, Guo, Austin M., Scicli, Guillermo, Arbab, Ali S.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280215/
https://ncbi.nlm.nih.gov/pubmed/25549350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116247
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