Broad Adaptive Immune Responses to M. tuberculosis Antigens Precede TST Conversion in Tuberculosis Exposed Household Contacts in a TB-Endemic Setting

BACKGROUND: The identification of Mycobacterium(-)tuberculosis (Mtb) infected individuals remains a challenge due to an insufficient understanding of immune responses detected with the current diagnostic tests for latent tuberculosis i.e. the tuberculin skin test (TST) or IFN–γ release assays (IGRAs...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Buchwald, Ulrike K., Adetifa, Ifedayo M. O., Bottomley, Christian, Owiafe, Patrick K., Donkor, Simon, Bojang, Adama L., Sutherland, Jayne S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280211/
https://ncbi.nlm.nih.gov/pubmed/25549338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116268
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