18F-FMISO PET/CT Visualization of Tumor Hypoxia in Patients with Chordoma of the Mobile and Sacrococcygeal Spine

Local recurrence (LR) rates in chordoma patients following surgery ± radiation therapy (RT) or definitive RT are high. Tumor hypoxia is associated with radioresistance and LR. In this prospective study, [(18)F]-FMISO-PET/CT detected hypoxic tumor sub-volumes in 60% of patients with chordoma of the m...

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I publikationen:Int J Radiat Oncol Biol Phys
Huvudupphovsmän: Cheney, Matthew D., Chen, Yen-Lin, Lim, Ruth, Winrich, Barbara K., Grosu, Anca L., Trofimov, Alexei V., Depauw, Nicolas, Shih, Helen A., Schwab, Joseph H., Hornicek, Francis J., DeLaney, Thomas F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280072/
https://ncbi.nlm.nih.gov/pubmed/25539367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2014.08.016
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