The GLP-1 Analogue Exenatide Improves Hepatic and Muscle Insulin Sensitivity in Diabetic Rats: Tracer Studies in the Basal State and during Hyperinsulinemic-Euglycemic Clamp

Objective. Glucagon-like peptide-1 (GLP-1) analogues (e.g., exenatide) increase insulin secretion in diabetes but less is known about their effects on glucose production or insulin-stimulated glucose uptake in peripheral tissues. Methods. Four groups of Sprague-Dawley rats were studied: nondiabetic...

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Veröffentlicht in:J Diabetes Res
Hauptverfasser: Wu, Hui, Sui, Chunhua, Xu, Hui, Xia, Fangzhen, Zhai, Hualing, Zhang, Huixin, Weng, Pan, Han, Bing, Du, Sichun, Lu, Yingli
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2014
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279913/
https://ncbi.nlm.nih.gov/pubmed/25580440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/524517
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