Spontaneous white matter damage, cognitive decline and neuroinflammation in middle-aged hypertensive rats: an animal model of early-stage cerebral small vessel disease

INTRODUCTION: Cerebral small vessel disease (cSVD) is one of the most prevalent neurological disorders. The progressive remodeling of brain microvessels due to arterial hypertension or other vascular risk factors causes subtle, but constant cognitive decline through to manifest dementia and substant...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Kaiser, Daniel, Weise, Gesa, Möller, Karoline, Scheibe, Johanna, Pösel, Claudia, Baasch, Sebastian, Gawlitza, Matthias, Lobsien, Donald, Diederich, Kai, Minnerup, Jens, Kranz, Alexander, Boltze, Johannes, Wagner, Daniel-Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279586/
https://ncbi.nlm.nih.gov/pubmed/25519173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-014-0169-8
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