SOX10, a novel HMG-box-containing tumor suppressor, inhibits growth and metastasis of digestive cancers by suppressing the Wnt/β-catenin pathway

SOX10 was identified as a methylated gene in our previous cancer methylome study. Here we further analyzed its epigenetic inactivation, biological functions and related cell signaling in digestive cancers (colorectal, gastric and esophageal cancers) in detail. SOX10 expression was decreased in multi...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Tong, Xin, Li, Lili, Li, Xiaoyan, Heng, Lei, Zhong, Lan, Su, Xianwei, Rong, Rong, Hu, Shi, Liu, Wenjia, Jia, Baoqing, Liu, Xing, Kou, Geng, Han, Jun, Guo, Shangjing, Hu, Yi, Li, Cheng, Tao, Qian, Guo, Yajun
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2014
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279394/
https://ncbi.nlm.nih.gov/pubmed/25301735
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