Notch signaling drives multiple myeloma induced osteoclastogenesis

Multiple myeloma (MM) is closely associated with bone destruction. Once migrated to the bone marrow, MM cells unbalance bone formation and resorption via the recruitment and maturation of osteoclast precursors. The Notch pathway plays a key role in different types of cancer and drives several biolog...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Colombo, Michela, Thümmler, Katja, Mirandola, Leonardo, Garavelli, Silvia, Todoerti, Katia, Apicella, Luana, Lazzari, Elisa, Lancellotti, Marialuigia, Platonova, Natalia, Akbar, Moeed, Chiriva-Internati, Maurizio, Soutar, Richard, Neri, Antonino, Goodyear, Carl S., Chiaramonte, Raffaella
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279381/
https://ncbi.nlm.nih.gov/pubmed/25257302
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