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Effects of kinesin-5 inhibition on dendritic architecture and microtubule organization

Kinesin-5 is a slow homotetrameric motor protein best known for its essential role in the mitotic spindle, where it limits the rate at which faster motors can move microtubules. In neurons, experimental suppression of kinesin-5 causes the axon to grow faster by increasing the mobility of microtubule...

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Bibliografiske detaljer
Udgivet i:Mol Biol Cell
Main Authors: Kahn, Olga I., Sharma, Vandana, González-Billault, Christian, Baas, Peter W.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279230/
https://ncbi.nlm.nih.gov/pubmed/25355946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-08-1313
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