KCHO-1, a Novel Antineuroinflammatory Agent, Inhibits Lipopolysaccharide-Induced Neuroinflammatory Responses through Nrf2-Mediated Heme Oxygenase-1 Expression in Mouse BV2 Microglia Cells

The brain is vulnerable to oxidative stress and inflammation that can occur as a result of aging or neurodegenerative diseases. Our work has sought to identify natural products that regulate heme oxygenase (HO)-1 and to determine their mechanism of action in neurodegenerative diseases. KCHO-1 is a n...

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Bibliografiske detaljer
Udgivet i:Evid Based Complement Alternat Med
Main Authors: Lee, Dong-Sung, Ko, Wonmin, Yoon, Chi-Su, Kim, Dong-Cheol, Yun, Jinju, Lee, Jun-Kyung, Jun, Ki-Young, Son, Ilhong, Kim, Dong-Woung, Song, Bong-Keun, Choi, Seulah, Jang, Jun-Hyeog, Oh, Hyuncheol, Kim, Sungchul, Kim, Youn-Chul
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279125/
https://ncbi.nlm.nih.gov/pubmed/25580149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/357154
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