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The Antipsoriatic Agent Monomethylfumarate Has Antiproliferative, Prodifferentiative, and Anti-Inflammatory Effects on Keratinocytes

Monomethylfumarate (MMF) is thought to be the bioactive ingredient of the drug Fumaderm (Biogen Idec, Cambridge, MA), licensed in Germany since 1994 for the treatment of moderate-to-severe psoriasis. Psoriasis is a common inflammatory hyperproliferative skin disorder that involves cross-talk between...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Helwa, Inas, Patel, Ravi, Karempelis, Peter, Kaddour-Djebbar, Ismail, Choudhary, Vivek, Bollag, Wendy B.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279100/
https://ncbi.nlm.nih.gov/pubmed/25332455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.218818
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