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Pan-neurotrophin 1: a genetically engineered neurotrophic factor displaying multiple specificities in peripheral neurons in vitro and in vivo.

Pan-neurotrophin 1 (PNT-1) is a synthetic trophic factor engineered by combining active domains of the neurotrophins nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophin 3 (NT-3) into an NT-3 backbone. This molecule was produced in transiently transfected COS cells o...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Ilag, L L, Curtis, R, Glass, D, Funakoshi, H, Tobkes, N J, Ryan, T E, Acheson, A, Lindsay, R M, Persson, H, Yancopoulos, G D
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42791/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7831338/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.2.607
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