Decreased expression of APAF-1 and increased expression of cathepsin B in invasive pituitary adenoma

PURPOSE: Apoptotic protease-activating factor-1 (APAF-1) and cathepsin B are important functional proteins in apoptosis; the former is involved in the intrinsic (mitochondrial) pathway, while the latter is associated with both intrinsic and extrinsic pathways. Changes in the expression of apoptosome...

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Bibliographic Details
Published in:Onco Targets Ther
Main Authors: Tanase, Cristiana, Albulescu, Radu, Codrici, Elena, Calenic, Bogdan, Popescu, Ionela Daniela, Mihai, Simona, Necula, Laura, Cruceru, Maria Linda, Hinescu, Mihail Eugen
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2014
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278787/
https://ncbi.nlm.nih.gov/pubmed/25565868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S70886
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