ADP-Ribosylation of NLRP3 by Mycoplasma pneumoniae CARDS Toxin Regulates Inflammasome Activity

The inflammasome is a major regulator of inflammation through its activation of procaspase-1, which cleaves prointerleukin-1β (pro-IL-1β) into its mature form. IL-1β is a critical proinflammatory cytokine that dictates the severity of inflammation associated with a wide spectrum of inflammatory dise...

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Bibliografski detalji
Izdano u:mBio
Glavni autori: Bose, Santanu, Segovia, Jesus A., Somarajan, Sudha R., Chang, Te-Hung, Kannan, T. R., Baseman, Joel B.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Microbiology 2014
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278538/
https://ncbi.nlm.nih.gov/pubmed/25538194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02186-14
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