ADP-Ribosylation of NLRP3 by Mycoplasma pneumoniae CARDS Toxin Regulates Inflammasome Activity

The inflammasome is a major regulator of inflammation through its activation of procaspase-1, which cleaves prointerleukin-1β (pro-IL-1β) into its mature form. IL-1β is a critical proinflammatory cytokine that dictates the severity of inflammation associated with a wide spectrum of inflammatory dise...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:mBio
Autores principales: Bose, Santanu, Segovia, Jesus A., Somarajan, Sudha R., Chang, Te-Hung, Kannan, T. R., Baseman, Joel B.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Microbiology 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278538/
https://ncbi.nlm.nih.gov/pubmed/25538194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02186-14
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares