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Methylated phenanthrenes are more potent than phenanthrene in a bioassay of human aryl hydrocarbon receptor (AhR) signaling

Alkylated polycyclic aromatic hydrocarbons (APAHs) are abundant in petroleum, but data regarding their toxicological properties are limited. A survey of all monomethylated phenanthrene structures revealed that they were 2 times to 5 times more potent than phenanthrene for activation of human aryl hy...

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Pubblicato in:Environ Toxicol Chem
Autori principali: Sun, Yue, Miller, Charles A, Wiese, Thomas E, Blake, Diane A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley Periodicals, Inc 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278532/
https://ncbi.nlm.nih.gov/pubmed/25043914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/etc.2687
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