Multiple Requirements of the Focal Dermal Hypoplasia Gene Porcupine during Ocular Morphogenesis

Wnt glycoproteins control key processes during development and disease by activating various downstream pathways. Wnt secretion requires post-translational modification mediated by the O-acyltransferase encoded by the Drosophila porcupine homolog gene (PORCN). In humans, PORCN mutations cause focal...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Pathol
Prif Awduron: Bankhead, Elizabeth J., Colasanto, Mary P., Dyorich, Kayla M., Jamrich, Milan, Murtaugh, L. Charles, Fuhrmann, Sabine
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Investigative Pathology 2015
Pynciau:
Regular Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278246/
https://ncbi.nlm.nih.gov/pubmed/25451153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.09.002
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