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Novel Roles for Caspase-8 in IL-1β and Inflammasome Regulation
Caspase-8 is an initiator and apical activator caspase that plays a central role in apoptosis. Caspase-8–deficient mice are embryonic lethal, which makes study of caspase-8 in primary immune cells difficult. Recent advances have rescued caspase-8–deficient mice by crossing them to mice deficient in...
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| 出版年: | Am J Pathol |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Investigative Pathology
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4278239/ https://ncbi.nlm.nih.gov/pubmed/25451151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.08.025 |
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