Saturation Mutagenesis of Burkholderia cepacia R34 2,4-Dinitrotoluene Dioxygenase at DntAc Valine 350 for Synthesizing Nitrohydroquinone, Methylhydroquinone, and Methoxyhydroquinone

Saturation mutagenesis of the 2,4-dinitrotoluene dioxygenase (DDO) of Burkholderia cepacia R34 at position valine 350 of the DntAc α-subunit generated mutant V350F with significantly increased activity towards o-nitrophenol (47 times), m-nitrophenol (34 times), and o-methoxyphenol (174 times) as wel...

Полное описание

Библиографические подробности

Опубликовано в::	Appl Environ Microbiol
Главные авторы:	Keenan, Brendan G., Leungsakul, Thammajun, Smets, Barth F., Wood, Thomas K.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 2004
Предметы:	Enzymology and Protein Engineering
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC427795/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15184115/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.70.6.3222-3231.2004
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!