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Aryl hydrocarbon receptor knock-out exacerbates choroidal neovascularization via multiple pathogenic pathways
The aryl hydrocarbon receptor (AhR) is a heterodimeric transcriptional regulator with pleiotropic functions in xenobiotic metabolism and detoxification, vascular development and cancer. Herein, we report a previously undescribed role for the AhR signalling pathway in the pathogenesis of the wet, neo...
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| Publié dans: | J Pathol |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley & Sons, Ltd
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4277859/ https://ncbi.nlm.nih.gov/pubmed/25186463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4433 |
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