Integrin α(v)β(3) as a PET Imaging Biomarker for Osteoclast Number in Mouse Models of Negative and Positive Osteoclast Regulation

PURPOSE: The goal of this study was to determine the specificity of (64)Cu-CB-TE2A-c(RGDyK) ((64)Cu-RGD) for osteoclast-related diseases, such as Paget's disease or rheumatoid arthritis. PROCEDURES: C57BL/6 mice were treated systemically with osteoprotegerin (OPG) for 15 days or RANKL for 11 da...

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Vydáno v:Mol Imaging Biol
Hlavní autoři: Zheleznyak, Alexander, Wadas, Thaddeus J., Sherman, Christopher D., Wilson, Jessica M., Kostenuik, Paul J., Weilbaecher, Katherine N., Anderson, Carolyn J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277818/
https://ncbi.nlm.nih.gov/pubmed/21853370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-011-0512-4
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