Specificity of lectin-immobilized fluorescent nanospheres for colorectal tumors in a mouse model which more resembles the clinical disease

We are investigating an imaging agent that enables real-time and accurate diagnosis of early colorectal cancer at the intestinal mucosa by colonoscopy. The imaging agent is peanut agglutinin-immobilized polystyrene nanospheres with surface poly(N-vinylacetamide) chains encapsulating coumarin 6. Intr...

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Detalhes bibliográficos
Publicado no:Contrast Media Mol Imaging
Main Authors: Kitamura, Tokio, Sakuma, Shinji, Shimosato, Moe, Higashino, Haruki, Masaoka, Yoshie, Kataoka, Makoto, Yamashita, Shinji, Hiwatari, Ken-ichiro, Kumagai, Hironori, Morimoto, Naoki, Koike, Seiji, Tobita, Etsuo, Hoffman, Robert M., Gore, John C., Pham, Wellington
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277738/
https://ncbi.nlm.nih.gov/pubmed/24976331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmmi.1609
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