Treatment of sporadic inclusion body myositis with bimagrumab

OBJECTIVE: To study activin signaling and its blockade in sporadic inclusion body myositis (sIBM) through translational studies and a randomized controlled trial. METHODS: We measured transforming growth factor β signaling by SMAD2/3 phosphorylation in muscle biopsies of 50 patients with neuromuscul...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Neurology
Päätekijät: Amato, Anthony A., Sivakumar, Kumaraswamy, Goyal, Namita, David, William S., Salajegheh, Mohammad, Praestgaard, Jens, Lach-Trifilieff, Estelle, Trendelenburg, Anne-Ulrike, Laurent, Didier, Glass, David J., Roubenoff, Ronenn, Tseng, Brian S., Greenberg, Steven A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Lippincott Williams & Wilkins 2014
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277670/
https://ncbi.nlm.nih.gov/pubmed/25381300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000001070
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