Phosphoinositide-3 Kinase Inhibition Modulates Responses to Rhinovirus by Mechanisms that Are Predominantly Independent of Autophagy

Human rhinoviruses (HRV) are a major cause of exacerbations of airways disease. Aspects of cell signalling responses to HRV infection remain unclear, particularly with regard to signalling via PI3K, and the PI3K-dependent pathway, autophagy. We investigated the roles of PI3K and autophagy in the res...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Ismail, Saila, Stokes, Clare A., Prestwich, Elizabeth C., Roberts, Rebecca L., Juss, Jatinder K., Sabroe, Ian, Parker, Lisa C.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2014
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277460/
https://ncbi.nlm.nih.gov/pubmed/25541728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116055
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