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Enhancement of Cry19Aa Mosquitocidal Activity against Aedes aegypti by Mutations in the Putative Loop Regions of Domain II
Improvements in the mosquitocidal activity of Bacillus thuringiensis Cry19Aa were achieved by protein engineering of putative surface loop residues in domain II through rational design. The improvement of Aedes toxicity in Cry19Aa was 42,000-fold and did not affect its toxicity against Anopheles or...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2004
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC427746/ https://ncbi.nlm.nih.gov/pubmed/15184189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.70.6.3769-3771.2004 |
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