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Assessment of [(125)I]WYE-230949 as a Novel Histamine H(3) Receptor Radiopharmaceutical

Histamine H(3) receptor therapeutics have been proposed for several diseases such as schizophrenia, attention deficit hyperactivity disorder, Alzheimer's disease and obesity. We set out to evaluate the novel compound, [(125)I]WYE-230949, as a potential radionuclide imaging agent for the histami...

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Pubblicato in:PLoS One
Autori principali: Lewis, David Y., Champion, Sue, Wyper, David, Dewar, Deborah, Pimlott, Sally
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277420/
https://ncbi.nlm.nih.gov/pubmed/25542008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115876
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