Detection of SRSF2-P95 Mutation by High-Resolution Melting Curve Analysis and Its Effect on Prognosis in Myelodysplastic Syndrome

Hotspot mutations of serine/arginine-rich splicing factor 2 (SRSF2) gene have been identified in a proportion of hematologic malignancies including myelodysplastic syndrome (MDS). The aim of the present study was to develop a new approach to screen SRSF2 mutation and analyze the clinical relevance o...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lin, Jiang, Yang, Jing, Wen, Xiang-mei, Yang, Lei, Deng, Zhao-qun, Qian, Zhen, Ma, Ji-chun, Guo, Hong, Zhang, Ying-ying, Qian, Wei, Qian, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277410/
https://ncbi.nlm.nih.gov/pubmed/25541999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115693
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