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Hydrophobin Fusion of an Influenza Virus Hemagglutinin Allows High Transient Expression in Nicotiana benthamiana, Easy Purification and Immune Response with Neutralizing Activity

The expression of recombinant hemagglutinin in plants is a promising alternative to the current egg-based production system for the influenza vaccines. Protein-stabilizing fusion partners have been developed to overcome the low production yields and the high downstream process costs associated with...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Jacquet, Nicolas, Navarre, Catherine, Desmecht, Daniel, Boutry, Marc
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277400/
https://ncbi.nlm.nih.gov/pubmed/25541987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115944
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