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Specific 12β-Hydroxylation of Cinobufagin by Filamentous Fungi
Biotransformation of natural products has great potential for producing new drugs and could provide in vitro models of mammalian metabolism. Microbial transformation of the cytotoxic steroid cinobufagin was investigated. Cinobufagin could be specifically hydroxylated at the 12β-position by the fungu...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC427727/ https://ncbi.nlm.nih.gov/pubmed/15184152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.70.6.3521-3527.2004 |
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