A quantitative framework to evaluate modeling of cortical development by neural stem cells

Neural stem cells have been adopted to model a wide range of neuropsychiatric conditions in vitro. However, how well such models correspond to in vivo brain has not been evaluated in an unbiased, comprehensive manner. We used transcriptomic analyses to compare in vitro systems to developing human fe...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Stein, Jason L., de la Torre-Ubieta, Luis, Tian, Yuan, Parikshak, Neelroop N., Hernandez, Israel A., Marchetto, Maria C., Baker, Dylan K., Lu, Daning, Hinman, Cassidy R., Lowe, Jennifer K., Wexler, Eric M., Muotri, Alysson R., Gage, Fred H., Kosik, Kenneth S., Geschwind, Daniel H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277209/
https://ncbi.nlm.nih.gov/pubmed/24991955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.05.035
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