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A Role for Saccharomyces cerevisiae Tpa1 Protein in Direct Alkylation Repair

Alkylating agents induce cytotoxic DNA base adducts. In this work, we provide evidence to suggest, for the first time, that Saccharomyces cerevisiae Tpa1 protein is involved in DNA alkylation repair. Little is known about Tpa1 as a repair protein beyond the initial observation from a high-throughput...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Shivange, Gururaj, Kodipelli, Naveena, Monisha, Mohan, Anindya, Roy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276862/
https://ncbi.nlm.nih.gov/pubmed/25381260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.590216
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