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A Role for Saccharomyces cerevisiae Tpa1 Protein in Direct Alkylation Repair
Alkylating agents induce cytotoxic DNA base adducts. In this work, we provide evidence to suggest, for the first time, that Saccharomyces cerevisiae Tpa1 protein is involved in DNA alkylation repair. Little is known about Tpa1 as a repair protein beyond the initial observation from a high-throughput...
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Publicado no: | J Biol Chem |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4276862/ https://ncbi.nlm.nih.gov/pubmed/25381260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.590216 |
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