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Hyperglycemia, p53 and mitochondrial pathway of apoptosis are involved in the susceptibility of diabetic models to ischemic acute kidney injury

Patients with chronic kidney diseases, including diabetic nephropathy, are more susceptible to acute kidney injury (AKI) and have a worse prognosis following AKI. However, the underlying mechanism is unclear. Here we tested whether diabetic mice were more sensitive to AKI and show that renal ischemi...

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Detalles Bibliográficos
Publicado en:Kidney Int
Main Authors: Peng, Jianping, Li, Xiaoning, Zhang, Dongshan, Chen, Jian-Kang, Su, Yunchao, Smith, Sylvia B., Dong, Zheng
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276728/
https://ncbi.nlm.nih.gov/pubmed/24963915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2014.226
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