Protective Effect of Quercetin on Melphalan-Induced Oxidative Stress and Impaired Renal and Hepatic Functions in Rat

One major challenge with the use of anticancer agents is the phenomenon of drug-induced toxicity. Melphalan (MPLN) is an alkylating anticancer agent, while quercetin (QCT) is an antioxidant. We investigated the protective role of quercetin against MPLN-induced toxicity. Twenty-five male Wistar rats...

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Опубликовано в: :Chemother Res Pract
Главные авторы: Olayinka, Ebenezer Tunde, Ore, Ayokanmi, Ola, Olaniyi Solomon, Adeyemo, Oluwatobi Adewumi
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2014
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276702/
https://ncbi.nlm.nih.gov/pubmed/25574394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/936526
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