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Comparison of antidepressant-like and abuse-related effects of phencyclidine in rats

NMDA receptor antagonists such as ketamine have emerged as novel candidate treatments for major depressive disorder, but abuse potential of these agents is a concern. The NMDA antagonist phencyclidine has known abuse liability but undefined efficacy as an antidepressant. To further evaluate the rela...

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Publicado en:Drug Dev Res
Autores principales: Hillhouse, Todd M., Porter, Joseph H., Negus, S. Stevens
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276473/
https://ncbi.nlm.nih.gov/pubmed/25315690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ddr.21228
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