Onset of multiple sclerosis before adulthood leads to failure of age-expected brain growth

OBJECTIVE: To determine the impact of pediatric-onset multiple sclerosis (MS) on age-expected brain growth. METHODS: Whole brain and regional volumes of 36 patients with relapsing-remitting MS onset prior to 18 years of age were segmented in 185 longitudinal MRI scans (2–11 scans per participant, 3-...

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Gepubliceerd in:Neurology
Hoofdauteurs: Aubert-Broche, Bérengère, Fonov, Vladimir, Narayanan, Sridar, Arnold, Douglas L., Araujo, David, Fetco, Dumitru, Till, Christine, Sled, John G., Banwell, Brenda, Collins, D. Louis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Lippincott Williams & Wilkins 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276405/
https://ncbi.nlm.nih.gov/pubmed/25378667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000001045
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