Ceramide synthase inhibitor fumonisin B1 inhibits apoptotic cell death in SCC17B human head and neck squamous carcinoma cells after Pc4 photosensitization

The sphingolipid ceramide modulates stress-induced cell death and apoptosis. We have shown that ceramide generated via de novo sphingolipid biosynthesis is required to initiate apoptosis after photodynamic therapy (PDT). The objective of this study was to define the role of ceramide synthase (CERS)...

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Detalhes bibliográficos
Publicado no:Photochem Photobiol Sci
Main Authors: Boppana, Nithin B., Kodiha, Mohamed, Stochaj, Ursula, Lin, Ho-sheng, Haimovitz-Friedman, Adrianna, Bielawska, Alicja, Bielawski, Jacek, Divine, George W., Boyd, John A., Korbelik, Mladen, Separovic, Duska
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276310/
https://ncbi.nlm.nih.gov/pubmed/25266739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4pp00292j
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