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Rho-kinase inhibition is involved in the activation of PI3-kinase/Akt during ischemic-preconditioning-induced cardiomyocyte apoptosis

We and others have reported that Rho-kinase plays an important role in the pathogenesis of heart ischemia/reperfusion (I/R) injury. Studies also have demonstrated that the activation of Rho-kinase was reversed in ischemic preconditioning (IPC). This study aimed to explain the mechanism of Rho-kinase...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Med
Main Authors: Zhang, Juan, Liu, Xiao-Bo, Cheng, Chao, Xu, Dong-Ling, Lu, Qing-Hua, Ji, Xiao-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276178/
https://ncbi.nlm.nih.gov/pubmed/25550920
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