Emergence of CD134 cysteine-rich domain 2 (CRD2)-independent strains of feline immunodeficiency virus (FIV) is associated with disease progression in naturally infected cats

BACKGROUND: Feline immunodeficiency virus (FIV) infection is mediated by sequential interactions with CD134 and CXCR4. Field strains of virus vary in their dependence on cysteine-rich domain 2 (CRD2) of CD134 for infection. FINDINGS: Here, we analyse the receptor usage of viral variants in the blood...

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Publicat a:Retrovirology
Autors principals: Bęczkowski, Paweł M, Techakriengkrai, Navapon, Logan, Nicola, McMonagle, Elizabeth, Litster, Annette, Willett, Brian J, Hosie, Margaret J
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Short Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275942/
https://ncbi.nlm.nih.gov/pubmed/25430586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-014-0095-7
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