Nucleotide Sequencing of DNA: Preliminary Characterization of the Products of Specific Cleavages at Guanine, Cytosine, or Adenine Residues

DNA synthesized in vitro from a phage M13 template has been cleaved at either guanine, adenine, or cytosine residues by ribosubstitution techniques. Fingerprints of the fragments obtained suggest that DNA sequencing will be possible with this technique.

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Bibliographic Details
Main Authors: Salser, Winston, Fry, Kirk, Brunk, Clifford, Poon, Raymond
Format: Artigo
Language:Inglês
Published: 1972
Subjects:
Biological Sciences: Biochemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC427583/
https://ncbi.nlm.nih.gov/pubmed/4500550
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