SOX10 Transactivates S100B to Suppress Schwann Cell Proliferation and to Promote Myelination

Schwann cells are an important cell source for regenerative therapy for neural disorders. We investigated the role of the transcription factor sex determining region Y (SRY)-box 10 (SOX10) in the proliferation and myelination of Schwann cells. SOX10 is predominantly expressed in rat sciatic nerve-de...

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Pubblicato in:PLoS One
Autori principali: Fujiwara, Sayaka, Hoshikawa, Shinya, Ueno, Takaaki, Hirata, Makoto, Saito, Taku, Ikeda, Toshiyuki, Kawaguchi, Hiroshi, Nakamura, Kozo, Tanaka, Sakae, Ogata, Toru
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275212/
https://ncbi.nlm.nih.gov/pubmed/25536222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115400
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