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Structural studies of a potent insect maturation inhibitor bound to the juvenile hormone esterase of Manduca sexta

Juvenile hormone (JH) is an insect hormone containing an α,β unsaturated ester consisting of a small alcohol and long, hydrophobic acid. JH degradation is required for proper insect development. One pathway of this degradation is through juvenile hormone esterase (JHE), which cleaves the JH ester bo...

Ausführliche Beschreibung

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Veröffentlicht in:Biochemistry
Hauptverfasser: Wogulis, Mark, Wheelock, Craig E., Kamita, Shizuo G., Hinton, Andrew C., Whetstone, Paul A., Hammock, Bruce D., Wilson, David K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275126/
https://ncbi.nlm.nih.gov/pubmed/16566578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0521644
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