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Automatic parameter estimation of multicompartmental neuron models via minimization of trace error with control adjustment

We describe a new technique to fit conductance-based neuron models to intracellular voltage traces from isolated biological neurons. The biological neurons are recorded in current-clamp with pink (1/f) noise injected to perturb the activity of the neuron. The new algorithm finds a set of parameters...

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Detalhes bibliográficos
Publicado no:J Neurophysiol
Main Authors: Brookings, Ted, Goeritz, Marie L., Marder, Eve
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274917/
https://ncbi.nlm.nih.gov/pubmed/25008414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00007.2014
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